PER1 antibody

Catalog No. ABIN289982

Product Details anti-PER1 Antibody

Target: PER1 (Period Homolog 1 (Drosophila) (PER1))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PER1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody was purified from rabbit serum by Protein G affinity chromatography.

Immunogen: GST-Rat PERIOD1 fusion Protein

Application Details

Restrictions: For Research Use only

Handling

Concentration: 1 mg/ml

Buffer: PBS (containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat)

Preservative: ProClin

Storage: -20 °C

Target Details for PER1

Target: PER1 (Period Homolog 1 (Drosophila) (PER1))

Alternative Name: PERIOD1 (PER1 Products)

Synonyms: PER antibody, RIGUI antibody, hPER antibody, per1 antibody, si:ch211-237l4.4 antibody, Per antibody, m-rigui antibody, mPer1 antibody, rper1 antibody, Rigui-like antibody, per4 antibody, zfper4 antibody, period circadian regulator 1 antibody, period circadian clock 1a antibody, period circadian clock 1 antibody, period homolog 1 (Drosophila) antibody, period circadian clock 1b antibody, PER1 antibody, per1a antibody, per1 antibody, Per1 antibody, per1b antibody

Background: Most organisms show circadian 24-h rhythmicity in their behavior and phsysiology. In mammals,biological clock is located in the suprachiasmatic nucleus (SCN), generates circadian rhythms in behaviourand physiology. These biological rhythms are adjusted daily to the environmental light/dark cycle via theretinohypothalamic tract (RHT). Three mammalian priod genes (per1, per2, and per3) that resemble theclock-regulating gene of Dorosophia melangaster, period (per ), have been cloned. Circadian clocks arealso located in peripheral tissues of mammals that are synchronized by the SCN. A molecular description ofthe mammalian circadian system has revealed that circadian oscillations may be a fundamental property ofmany cells in the body.The nuclear entry of the circadian regulator mPER1 is controlled by mammalian casein kinase Iepsilon. Thisantibody is useful tool to clarify molecular functions that regulate biological clock.

Pathways: Photoperiodism