AJUBA antibody

Catalog No. ABIN290002

Product Details anti-AJUBA Antibody

Target: AJUBA (Ajuba LIM Protein (AJUBA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AJUBA antibody is un-conjugated

Application: Immunoprecipitation (IP), Immunocytochemistry (ICC)

Purification: This antibody was purified from rabbit serum by affinity chromatography.

Immunogen: GST-Human Ajuba fusion Protein

Application Details

Application Notes: Working dilution For Immunoprecipitation , 10 ug/mlFor Immnocytochemistry , 2-5 ug/ml

Restrictions: For Research Use only

Handling

Concentration: 0.25 mg/ml

Buffer: PBS (containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat)

Preservative: ProClin

Storage: -20 °C

Target Details for AJUBA

Target: AJUBA (Ajuba LIM Protein (AJUBA))

Alternative Name: Ajuba (AJUBA Products)

Synonyms: JUB antibody, Jub antibody, ajuba LIM protein antibody, AJUBA antibody, Ajuba antibody

Background: Aurora-A(Aurora-A/STK-15/Aik) encoding a centrosome-associated Ser/Thr kinase, is amplified andoverexpressed in many cancer cell types, and is involved in the induction of centrosomeduplication-distribution abnormalities and aneuploidy in mammalian cells. In vitro transformation activityof Aurora-A suggested to be a potential oncogene. Recent research elucidated that Ajuba, Aurora-A bindingprotein, induces the autophosphorylation and consequent activation of Aurora-A . In the future thisantibody will contribute the research progress whether Ajuba and Aurora-A are involed in tumorigenesis.This antibody is useful for immunoprecipitation and immunocytochemistry.

Pathways: Chromatin Binding, Cell-Cell Junction Organization