ENPP2 antibody

Catalog No. ABIN290037

Product Details anti-ENPP2 Antibody

Target: ENPP2 (Ectonucleotide Pyrophosphatase/phosphodiesterase 2 (ENPP2))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ENPP2 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: This antibody was established from the serum of a rabbit immunized with a peptiderepresenting the N-terminal domain of Autotaxin.Purified by peptide affinity chromatography.

Immunogen: Partial peptide of Autotaxin (N-Term)

Application Details

Application Notes: Working dilution For Western blotting:0.5ug/ml

Restrictions: For Research Use only

Handling

Concentration: 0.1 mg/ml

Buffer: PBS (containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat)

Preservative: ProClin

Storage: -20 °C

Target Details for ENPP2

Target: ENPP2 (Ectonucleotide Pyrophosphatase/phosphodiesterase 2 (ENPP2))

Alternative Name: Autotaxin (ENPP2 Products)

Synonyms: ATX antibody, ATX-X antibody, AUTOTAXIN antibody, LysoPLD antibody, NPP2 antibody, PD-IALPHA antibody, PDNP2 antibody, Npps2 antibody, PD-Ialpha antibody, Pdnp2 antibody, MGC132047 antibody, atx antibody, zgc:63550 antibody, autotaxin antibody, enpp2 antibody, enpp2a antibody, enpp2b antibody, ectonucleotide pyrophosphatase/phosphodiesterase 2 antibody, ectonucleotide pyrophosphatase/phosphodiesterase 2 L homeolog antibody, ectonucleotide pyrophosphatase/phosphodiesterase 2 S homeolog antibody, ENPP2 antibody, Enpp2 antibody, enpp2 antibody, enpp2.L antibody, enpp2.S antibody

Background: Autotaxin, a member of the ENPP (Ectonucleotide pyrophospatase/phosphodiesterase) family ofectoenzymes, was originally identified as a motogen secreted by a melanoma cell line and subsequentlyreported to promote cell proliferation, cell motility, angiogenesis, and neurite retraction. Autotaxin haslysophospholipase D activity and appears to exert its effects by generation of the lipid mediatorlysophosphatidic acid (LPA) from lysophosphatidylcholine and sphingosine 1-phosphate (S1P) fromsphingosylphosphorylcholine (SPC) outside the cell.Autotaxin levels are significantly higher in cancerous tissues than in normal tissues suggesting that thisnovel extracellular protein may be involved in tumor progression.Two Autotaxin antibodies are available,KM105: Specifically reacts with a C-terminal fragment of AutotaxinKM106: Specifically reacts with an N-terminal fragment of Autotaxin