Bax Inhibitor 1 antibody

Catalog No. ABIN290214

The Mouse Monoclonal anti-Bax Inhibitor 1 antibody (Clone 20F430) (ABIN290214) specifically detects Bax Inhibitor 1 in IHC and IHC (p). The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for Bax Inhibitor 1 antibody (ABIN290214)

Target: Bax Inhibitor 1 (TMBIM6) (Transmembrane BAX Inhibitor Motif Containing 6 (TMBIM6))

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This Bax Inhibitor 1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 20F430

Product Details anti-Bax Inhibitor 1 Antibody

Specificity: A mixture of three synthetic peptides corresponding to the N-terminal, internal and C-terminal regions of human Bax Inhibitor 1. Epitope mapping indicates that the antibody recognizes an epitope in the N-terminal region of Bi-1.

Purification: Protein G purified

Immunogen: Synthetic peptide from human TMBIM6 / Bax Inhibitor 1.

Type of Immunogen: Synthetic peptide

Isotype: IgG2b

Application Details

Application Notes: Approved: IHC, IHC-P (5 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 5 μg/mL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.2 % gelatin, 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: 4°C or -20°C, Avoid freeze-thaw cycles.

Target Details for Bax Inhibitor 1

Target: Bax Inhibitor 1 (TMBIM6) (Transmembrane BAX Inhibitor Motif Containing 6 (TMBIM6))

Alternative Name: TMBIM6 / Bax Inhibitor 1

Background: Name/Gene ID: TMBIM6

Synonyms: TMBIM6, BI1, Bax inhibitor 1, BAXI1, BI-1, TEGT

Gene ID: 7009

UniProt: P55061

Pathways: Response to Water Deprivation, ER-Nucleus Signaling