HMGB1 antibody (acLys12)

Catalog No. ABIN7304162

The Rabbit Polyclonal anti-HMGB1 antibody (ABIN7304162) specifically detects HMGB1 in WB. The antibody is reactive with Human, Mouse, Rat, Cow, Dog, Monkey, Pig and Chicken samples.

Quick Overview for HMGB1 antibody (acLys12) (ABIN7304162)

Target: HMGB1 (High Mobility Group Box 1 (HMGB1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Monkey, Pig, Chicken

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HMGB1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HMGB1 Antibody

Binding Specificity: acLys12

Purpose: Rabbit polyclonal antibody to HMGB1 (Acetyl-K12)

Specificity: Recognizes endogenous levels of HMGB1 protein only when acetylated at K12.

Characteristics: Rabbit polyclonal antibody to HMGB1 (AcK12)

Purification: The antibody was purified by immunogen affinity chromatography.

Immunogen: KLH-conjugated synthetic acetylated peptide corresponding to residues surrounding K12 of human HMGB1 protein. The exact sequence is proprietary.

Application Details

Application Notes: WB (1/500 - 1/1000)

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid in 0.42 % Potassium phosphate, 0.87 % Sodium chloride, pH 7.3, 30 % glycerol, and 0.01 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.

Expiry Date: 12 months

Target Details for HMGB1

Target: HMGB1 (High Mobility Group Box 1 (HMGB1))

Alternative Name: HMGB1

Background: HMG1, High mobility group protein B1, High mobility group protein 1, HMG-1

Gene ID: 3146, 100862258, 25459

UniProt: P09429

Pathways: p53 Signaling, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Toll-Like Receptors Cascades, Smooth Muscle Cell Migration, Inflammasome