FGFR1b antibody (Ectodomain, Pro23)

Catalog No. ABIN2961626

Product Details anti-FGFR1b Antibody

Target: FGFR1b (Fibroblast Growth Factor Receptor 1 beta (FGFR1b))

Binding Specificity: Ectodomain, Pro23

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Application: Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)

Specificity: Reacts with human Fibroblast Growth Factor Receptor 1 beta (FGFR1β). Epitope is undetermined but presumed to be near junction of the common FGFr1 NH2-terminus and NH2-terminus of Ig loop II.

Purification: Purified (protein G)

Immunogen: Recombinant human ectodomain of FGFr1beta expressed in E. coli beginning with pro23, antigen contained NH2-terminal gly-ser-pro-gly-ile and COOH-terminal glu-phe sequences.

Clone: M17A3

Isotype: IgG2b

Application Details

Application Notes: Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
WB(1 μg/mL)

Restrictions: For Research Use only

Handling

Buffer: PBS, pH 7.4.

Handling Advice: Dilute in PBS or medium that is identical to that used in the assay system.

Storage: -20 °C/-80 °C

Storage Comment: Stable for at least one year at -20°C to -70°C. Avoid multiple freeze-thaw cycles.

Expiry Date: 12 months

Target Details for FGFR1b

Target: FGFR1b (Fibroblast Growth Factor Receptor 1 beta (FGFR1b))

Background: Fibroblast Growth Factor Receptor 1 (FGFR1) is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. This protein is a Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of embryonic development, cell proliferation, differentiation and migration.

FGFR-1 Basic fibroblast growth factor receptor 1, BFGFR, bFGF-R-1 Fms-like tyrosine kinase 2, FLT-2 N-sam Proto-oncogene c-Fgr CD_antigen : CD331 CEK FLG HH2 OGD KAL2 HBGFR HRTFDS Gene name : FGFR1

Gene ID: 2260

UniProt: P11362