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CHD3 antibody
CHD3
Reactivity: Human, Mouse
WB, IHC, ELISA, FACS, IF/ICC
Host: Mouse
Monoclonal
unconjugated
Product Details anti-CHD3 Antibody
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Target
See all CHD3 Antibodies
CHD3
(Chromodomain Helicase DNA Binding Protein 3 (CHD3))
Reactivity
All reactivities for CHD3 antibodies
Human, Mouse
Host
All hosts for CHD3 antibodies
Mouse
Clonality
All clonalities for CHD3 antibodies
Monoclonal
Conjugate
All conjugates for CHD3 antibodies
This CHD3 antibody is un-conjugated
Application
All applications for CHD3 antibodies
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunofluorescence (fixed cells) (IF/ICC)
Immunogen
Purified recombinant fragment of human CHD3 expressed in E. Coli.
Isotype
IgG1
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1.0 mg/mL
Buffer
Ascitic fluid containing 0.03 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
Target Details for CHD3
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Target
CHD3
(Chromodomain Helicase DNA Binding Protein 3 (CHD3))
Alternative Name
CHD3 (CHD3 Products )
Synonyms
CG9594 antibody, CHD-3 antibody, CHD3 antibody, DmCHD3 antibody, Dmel\\CG9594 antibody, chd3 antibody, dCHD3 antibody, LOC568230 antibody, zfh antibody, mi-2a antibody, mi2-alpha antibody, Mi-2a antibody, Mi2-ALPHA antibody, ZFH antibody, 2600010P09Rik antibody, AF020312 antibody, Chd7 antibody, Prp7 antibody, Prp9-1 antibody, CG9594 gene product from transcript CG9594-RA antibody, chromodomain helicase DNA binding protein 3 antibody, chromodomain-helicase-DNA-binding protein 3 antibody, Chd3 antibody, CHD3 antibody, chd3 antibody, LOC100480350 antibody
Background
This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described.
Molecular Weight
226 kDa
Gene ID
1107
UniProt
Q12873
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