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Metabotropic Glutamate Receptor 3 antibody (AA 23-170)
GRM3
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-Metabotropic Glutamate Receptor 3 Antibody
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Target
See all Metabotropic Glutamate Receptor 3 (GRM3) Antibodies
Metabotropic Glutamate Receptor 3 (GRM3)
(Glutamate Receptor, Metabotropic 3 (GRM3))
Binding Specificity
All epitopes for Metabotropic Glutamate Receptor 3 antibodies
AA 23-170
Reactivity
All reactivities for Metabotropic Glutamate Receptor 3 antibodies
Human
Host
All hosts for Metabotropic Glutamate Receptor 3 antibodies
Rabbit
Clonality
All clonalities for Metabotropic Glutamate Receptor 3 antibodies
Polyclonal
Conjugate
All conjugates for Metabotropic Glutamate Receptor 3 antibodies
This Metabotropic Glutamate Receptor 3 antibody is un-conjugated
Application
All applications for Metabotropic Glutamate Receptor 3 antibodies
Western Blotting (WB)
Sequence
LGDHNFLRRE IKIEGDLVLG GLFPINEKGT GTEECGRINE DRGIQRLEAM LFAIDEINKD DYLLPGVKLG VHILDTCSRD TYALEQSLEF VRASLTKVDE AEYMCPDGSY AIQENIPLLI AGVIGGSYSS VSIQVANLLR LFQIPQIS
Cross-Reactivity
Human, Mouse
Characteristics
Polyclonal Antibodies
Purification
Affinity purification
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 23-170 of human GRM3 (NP_000831.2).
Isotype
IgG
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Discover our top product GRM3 Primary Antibody
Alternatives
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anti-Glutamate Receptor, Metabotropic 3 (GRM3) (N-Term) antibody
GRM3
Reactivity: Human, Mouse, Rat, Cow, Horse, Monkey, Pig, Hamster
IHC, ICC, IHC (p)
Host: Rabbit
Polyclonal
unconjugated
anti-Glutamate Receptor, Metabotropic 3 (GRM3) (Extracellular Domain) antibody
GRM3
Reactivity: Human, Mouse, Rat, Cow, Horse, Monkey, Pig, Hamster, Orang-Utan, Gorilla
ICC, IHC (p)
Host: Rabbit
Polyclonal
unconjugated
Application Details
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Application Notes
WB,1:500 - 1:2000
Restrictions
For Research Use only
Handling
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Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for Metabotropic Glutamate Receptor 3
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Target
Metabotropic Glutamate Receptor 3 (GRM3)
(Glutamate Receptor, Metabotropic 3 (GRM3))
Alternative Name
GRM3 (GRM3 Products )
Synonyms
GLUR3 antibody, GPRC1C antibody, MGLUR3 antibody, mGlu3 antibody, 0710001G23Rik antibody, Gprc1c antibody, mGluR3 antibody, glutamate metabotropic receptor 3 antibody, glutamate receptor, metabotropic 3 antibody, GRM3 antibody, Grm3 antibody
Background
L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.,GRM3,GLUR3,GPRC1C,MGLUR3,mGlu3,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Neuroscience,GRM3
Molecular Weight
60 kDa/98 kDa
Gene ID
2913
UniProt
Q14832
Pathways
cAMP Metabolic Process , Synaptic Membrane
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