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ATF4 antibody (AA 1-351)
ATF4
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-ATF4 Antibody
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Target
See all ATF4 Antibodies
ATF4
(Activating Transcription Factor 4 (Tax-Responsive Enhancer Element B67) (ATF4))
Binding Specificity
All epitopes for ATF4 antibodies
AA 1-351
Reactivity
All reactivities for ATF4 antibodies
Human
Host
All hosts for ATF4 antibodies
Rabbit
Clonality
All clonalities for ATF4 antibodies
Polyclonal
Conjugate
All conjugates for ATF4 antibodies
This ATF4 antibody is un-conjugated
Application
All applications for ATF4 antibodies
Western Blotting (WB)
Sequence
MTEMSFLSSE VLVGDLMSPF DQSGLGAEES LGLLDDYLEV AKHFKPHGFS SDKAKAGSSE WLAVDGLVSP SNNSKEDAFS GTDWMLEKMD LKEFDLDALL GIDDLETMPD DLLTTLDDTC DLFAPLVQET NKQPPQTVNP IGHLPESLTK PDQVAPFTFL QPLPLSPGVL SSTPDHSFSL ELGSEVDITE GDRKPDYTAY VAMIPQCIKE EDTPSDNDSG ICMSPESYLG SPQHSPSTRG SPNRSLPSPG VLCGSARPKP YDPPGEKMVA AKVKGEKLDK KLKKMEQNKT AATRYRQKKR AEQEALTGEC KELEKKNEAL KERADSLAKE IQYLKDLIEE VRKARGKKRV P
Cross-Reactivity
Human
Characteristics
Polyclonal Antibodies
Purification
Affinity purification
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-351 of human ATF4 (NP_001666.2).
Isotype
IgG
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Discover our top product ATF4 Primary Antibody
Alternatives
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anti-Activating Transcription Factor 4 (Tax-Responsive Enhancer Element B67) (ATF4) (AA 251-351) antibody
ATF4
Reactivity: Human, Mouse, Rat, Dog, Rabbit
WB, ELISA, IHC (p), IF (cc), IF (p), FACS, IHC (fro)
Host: Rabbit
Polyclonal
unconjugated
Application Details
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Application Notes
WB,1:500 - 1:2000
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid freeze / thaw cycles
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
References for anti-ATF4 antibody (ABIN3020669)
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Li, Chen, Yang, Wang, Lin, Xu : "Selenoprotein S silencing triggers mouse hepatoma cells apoptosis and necrosis involving in intracellular calcium imbalance and ROS-mPTP-ATP. " in: Biochimica et biophysica acta. General subjects , Vol. 1862 , Issue 10 , pp. 2113-2123 , (2018 ) (PubMed ).
Target Details for ATF4
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Target
ATF4
(Activating Transcription Factor 4 (Tax-Responsive Enhancer Element B67) (ATF4))
Alternative Name
ATF4 (ATF4 Products )
Synonyms
CREB-2 antibody, CREB2 antibody, TAXREB67 antibody, TXREB antibody, ATF4 antibody, atf-4 antibody, creb-2 antibody, creb2 antibody, taxreb67 antibody, txreb antibody, atf4 antibody, wu:fj01c08 antibody, wu:fk30b04 antibody, zgc:85951 antibody, sb:eu681 antibody, wu:fb08f07 antibody, zgc:171702 antibody, Atf-4 antibody, C/ATF antibody, ATF4-I antibody, atf4-a antibody, atf4-b antibody, atf4-ii antibody, activating transcription factor 4 antibody, activating transcription factor 4 L homeolog antibody, activating transcription factor 4a antibody, activating transcription factor 4b antibody, activating transcription factor 4 S homeolog antibody, ATF4 antibody, atf4 antibody, Atf4 antibody, atf4.L antibody, atf4a antibody, atf4b antibody, atf4.S antibody
Background
This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromosome at q28 in a region containing a large inverted duplication.,ATF4,CREB-2,CREB2,TAXREB67,TXREB,Epigenetics & Nuclear Signaling,Transcription Factors,Signal Transduction,MAPK-Erk Signaling Pathway,Cell Biology & Developmental Biology,Protein folding,ATF4
Molecular Weight
38 kDa
Gene ID
468
UniProt
P18848
Pathways
Thyroid Hormone Synthesis , Myometrial Relaxation and Contraction , ER-Nucleus Signaling , Unfolded Protein Response
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