Pro-Glucagon (AA 21-180) antibody
Reactivity: Human
IF, IHC
Host: Rabbit
Polyclonal
unconjugated
-
- Target
- Pro-Glucagon
- Binding Specificity
- AA 21-180
- Reactivity
- Human
- Host
- Rabbit
- Clonality
- Polyclonal
- Application
- Immunofluorescence (IF), Immunohistochemistry (IHC)
- Sequence
- RSLQDTEEKS RSFSASQADP LSDPDQMNED KRHSQGTFTS DYSKYLDSRR AQDFVQWLMN TKRNRNNIAK RHDEFERHAE GTFTSDVSSY LEGQAAKEFI AWLVKGRGRR DFPEEVAIVE ELGRRHADGS FSDEMNTILD NLAARDFINW LIQTKITDRK
- Cross-Reactivity
- Human, Mouse, Rat
- Characteristics
- Polyclonal Antibodies
- Purification
- Affinity purification
- Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 21-180 of human Pro-glucagon (NP_002045.1).
- Isotype
- IgG
-
- Application Notes
- IHC,1:100 - 1:200,IF,1:100 - 1:200
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid freeze / thaw cycles
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze / thaw cycles.
-
- Target
- Pro-Glucagon
- Background
- The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon.,GCG,GLP-1,GLP1,GLP2,GRPP,glucagon,Cancer,Signal Transduction,Endocrine & Metabolism,Endocrine and metabolic diseases,Diabetes,Neuroscience,Stem Cells,Cardiovascular,Heart,Cardiovascular diseases,Heart disease,Pro-glucagon
- Molecular Weight
- 20 kDa
- Gene ID
- 2641
- UniProt
- P01275
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