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CDC45 antibody (AA 1-270)
CDC45
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-CDC45 Antibody
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Target
See all CDC45 Antibodies
CDC45
(Cell Division Cycle 45 Homolog (S. Cerevisiae) (CDC45))
Binding Specificity
All epitopes for CDC45 antibodies
AA 1-270
Reactivity
All reactivities for CDC45 antibodies
Human
Host
All hosts for CDC45 antibodies
Rabbit
Clonality
All clonalities for CDC45 antibodies
Polyclonal
Conjugate
All conjugates for CDC45 antibodies
This CDC45 antibody is un-conjugated
Application
All applications for CDC45 antibodies
Western Blotting (WB)
Sequence
MFVSDFRKEF YEVVQSQRVL LFVASDVDAL CACKILQALF QCDHVQYTLV PVSGWQELET AFLEHKEQFH YFILINCGAN VDLLDILQPD EDTIFFVCDT HRPVNVVNVY NDTQIKLLIK QDDDLEVPAY EDIFRDEEED EEHSGNDSDG SEPSEKRTRL EEEIVEQTMR RRQRREWEAR RRDILFDYEQ YEYHGTSSAM VMFELAWMLS KDLNDMLWWA IVGLTDQWVQ DKITQMKYVT DVGVLQRHVS RHNHRNEDEE NTLSVDCTRI
Cross-Reactivity
Human, Mouse, Rat
Characteristics
Polyclonal Antibodies
Purification
Affinity purification
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human CDC45 (NP_003495.1).
Isotype
IgG
Top Product
Discover our top product CDC45 Primary Antibody
Alternatives
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Application Details
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Application Notes
WB,1:500 - 1:2000
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid freeze / thaw cycles
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for CDC45
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Target
CDC45
(Cell Division Cycle 45 Homolog (S. Cerevisiae) (CDC45))
Alternative Name
CDC45 (CDC45 Products )
Synonyms
cdc45l antibody, cdc45l2 antibody, porc-pi-1 antibody, CDC45L antibody, CDC45L2 antibody, PORC-PI-1 antibody, Cdc45l antibody, cell division cycle 45 antibody, cell division cycle 45 S homeolog antibody, cell division cycle 45 L homeolog antibody, cdc45 antibody, CDC45 antibody, cdc45.S antibody, Cdc45 antibody, cdc45.L antibody
Background
The protein encoded by this gene was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA replication. Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18, the minichromosome maintenance proteins (MCMs) and DNA polymerase, which is important for early steps of DNA replication in eukaryotes. This protein has been shown to interact with MCM7 and DNA polymerase alpha. Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin. Alternate splicing results in multiple transcript variants.,CDC45,CDC45L,CDC45L2,MGORS7,PORC-PI-1,cdc45,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Cell Cycle,CDC45
Molecular Weight
60 kDa/65 kDa/68 kDa
Gene ID
8318
UniProt
O75419
Pathways
Mitotic G1-G1/S Phases , DNA Replication , Synthesis of DNA
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