CDKN1C antibody (AA 1-100)

Catalog No. ABIN3022819

The Rabbit Polyclonal anti-CDKN1C antibody is suitable to detect CDKN1C in samples from Human. It has been validated for WB.

Quick Overview for CDKN1C antibody (AA 1-100) (ABIN3022819)

Target: CDKN1C (Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDKN1C antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CDKN1C Antibody

Binding Specificity: AA 1-100

Sequence: MSDASLRSTS TMERLVARGT FPVLVRTSAC RSLFGPVDHE ELSRELQARL AELNAEDQNR WDYDFQQDMP LRGPGRLQWT EVDSDSVPAF YRETVQVGRC

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CDKN1C/p57 Kip2 (NP_000067.1).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CDKN1C

Target: CDKN1C (Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C))

Alternative Name: CDKN1C

Background: This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.,CDKN1C,BWCR,BWS,KIP2,WBS,p57,p57Kip2,Epigenetics & Nuclear Signaling,Cancer,Signal Transduction,Kinase,Cell Biology & Developmental Biology,Cell Cycle,Cell cycle inhibitors,CDKN1C

Molecular Weight: 31 kDa/32 kDa

Gene ID: 1028

UniProt: P49918

Pathways: Cell Division Cycle, Dopaminergic Neurogenesis