CDKN1C antibody

Catalog No. ABIN7193625

The Mouse Monoclonal anti-CDKN1C antibody (Clone 8G5D5) (ABIN7193625) specifically detects CDKN1C in WB, ELISA, FACS and IHC. The antibody is reactive with Human samples.

Quick Overview for CDKN1C antibody (ABIN7193625)

Target: CDKN1C (Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CDKN1C antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (IHC)

Clone: 8G5D5

Product Details anti-CDKN1C Antibody

Purpose: CDKN1C Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human CDKN1C expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200-1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target Details for CDKN1C

Target: CDKN1C (Cyclin-Dependent Kinase Inhibitor 1C (p57, Kip2) (CDKN1C))

Alternative Name: CDKN1C

Background:

This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.

Molecular Weight: 32.2 kDa

UniProt: P49918

Pathways: Cell Division Cycle, Dopaminergic Neurogenesis