PLK1 antibody (AA 304-603)

Catalog No. ABIN3023352

This Rabbit Polyclonal antibody specifically detects PLK1 in WB, IHC and IF. It exhibits reactivity toward Human.

Quick Overview for PLK1 antibody (AA 304-603) (ABIN3023352)

Target: PLK1 (Polo-Like Kinase 1 (PLK1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLK1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-PLK1 Antibody

Binding Specificity: AA 304-603

Sequence: FFTSGYIPAR LPITCLTIPP RFSIAPSSLD PSNRKPLTVL NKGLENPLPE RPREKEEPVV RETGEVVDCH LSDMLQQLHS VNASKPSERG LVRQEEAEDP ACIPIFWVSK WVDYSDKYGL GYQLCDNSVG VLFNDSTRLI LYNDGDSLQY IERDGTESYL TVSSHPNSLM KKITLLKYFR NYMSEHLLKA GANITPREGD ELARLPYLRT WFRTRSAIIL HLSNGSVQIN FFQDHTKLIL CPLMAAVTYI DEKRDFRTYR LSLLEEYGCC KELASRLRYA RTMVDKLLSS RSASNRLKAS

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 304-603 of human PLK1 (NP_005021.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid freeze / thaw cycles

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PLK1

Target: PLK1 (Polo-Like Kinase 1 (PLK1))

Alternative Name: PLK1

Background: The Ser/Thr protein kinase encoded by this gene belongs to the CDC5/Polo subfamily. It is highly expressed during mitosis and elevated levels are found in many different types of cancer. Depletion of this protein in cancer cells dramatically inhibited cell proliferation and induced apoptosis, hence, it is a target for cancer therapy.,PLK1,PLK,STPK13,Epigenetics & Nuclear Signaling,Cancer,Signal Transduction,Kinase,Serine/threonine kinases,Cell Biology & Developmental Biology,Cell Cycle,Centrosome,G2/M DNA Damage Checkpoint,PLK1

Molecular Weight: 68 kDa

Gene ID: 5347

UniProt: P53350

Pathways: Cell Division Cycle, M Phase