CD4 antibody

Catalog No. ABIN3024369

The Mouse Monoclonal anti-CD4 antibody is suitable to detect CD4 in samples from Human. It has been validated for FACS and IF.

Quick Overview for CD4 antibody (ABIN3024369)

Target: CD4

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD4 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: C4-206

Product Details anti-CD4 Antibody

Purification: Protein G affinity chromatography

Immunogen: Recombinant human CD4 protein was used as immunogen for the CD4 antibody.

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal dilution of the CD4 antibody for a specific application should be determined by researcher.\. Flow Cytometry: 0.5-1 μg/10e6 cells,Immunofluorescence: 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: CD4 antibody with azide can be stored at 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Target Details for CD4

Target: CD4

Alternative Name: CD4

Background: CD4 is a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigens and is also a receptor for the human immunodeficiency virus. This protein is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.

Pathways: TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events