DPP4 antibody

Catalog No. ABIN3025647

The Mouse Monoclonal anti-DPP4 antibody has been validated for FACS, IHC (fro) and IF. It is suitable to detect DPP4 in samples from Human and Rat.

Quick Overview for DPP4 antibody (ABIN3025647)

Target: DPP4 (Dipeptidyl-Peptidase 4 (DPP4))

Reactivity: Human, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This DPP4 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF)

Clone: 202-36

Product Details anti-DPP4 Antibody

No Cross-Reactivity: Pig (Porcine), Sheep (Ovine)

Purification: Protein G affinity chromatography

Immunogen: A human T cell clone was used as the immunogen for the CD26 antibody.

Isotype: IgG2b kappa

Application Details

Application Notes: Optimal dilution of the CD26 antibody should be determined by the researcher.\. Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,Immunofluorescence: 0.5-1 μg/mL,Immunohistochemistry (Frozen Only): 0.5-1 μg/mL for 30 min at RT

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Store the CD26 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Target Details for DPP4

Target: DPP4 (Dipeptidyl-Peptidase 4 (DPP4))

Alternative Name: CD26

Background: Recognizes a glycoprotein of 110  kDa, identified as CD26 (Workshop VI, Code: N-L039). It is an atypical serine protease belonging to the prolyl oligopeptidase family. It is expressed on lymphocyte cells and is upregulated during T-cell activation. CD26 is also expressed on activated B cells and natural killer cells and abundantly on epithelia. CD26 is implicated in a variety of biological functions including T-cell activation, cell adhesion with extracellular matrix such as fibronectin or collagens, and in HIV infection. Cross-linking of CD26 using this antibody dramatically enhances the anti-CD3-induced IL-2 production. In Western blotting, this mAb reacts with only glycosylated CD26, but not with the deglycosylated form. It does not prevent ADA binding to CD26.

Pathways: Peptide Hormone Metabolism, Regulation of Leukocyte Mediated Immunity