CD22 antibody

Catalog No. ABIN3025757

This Mouse Monoclonal antibody specifically detects CD22 in FACS. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for CD22 antibody (ABIN3025757)

Target: CD22 (CD22 Molecule (CD22))

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD22 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Grade: Carrier-free

Clone: MYG13

Product Details anti-CD22 Antibody

Purpose: CD22 Antibody (azide and preservative free)

Purification: Protein G affinity chromatography

Immunogen: Human Raji cells were used as the immunogen for the CD22 antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the CD22 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Store the CD22 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for CD22

Target: CD22 (CD22 Molecule (CD22))

Alternative Name: CD22

Background: Recognizes a protein of 130-140 kDa, identified as CD22 (also known as BL-CAM). CD22 expression is restricted to normal and neoplastic B cells and is absent from other haemopoietic cell types. In B-cell ontogeny, CD22 is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface as B cells mature to become IgD+. It is not expressed by plasma cells, CD22 is found highly expressed in follicular mantle and marginal zone B-cells, and while germinal center B-cells are relatively weak. CD22 is a member of the immunoglobulin superfamily and serves as an adhesion receptor for sialic acid-bearing ligands expressed on erythrocytes and all leukocyte classes. It also associates with tyrosine kinases and play a role in signal transduction and B-cell activation.

UniProt: P20273