TRAF4 antibody (C-Term)

Catalog No. ABIN3029153

Product Details anti-TRAF4 Antibody

Target: TRAF4 (TNF Receptor-Associated Factor 4 (TRAF4))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRAF4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Antigen affinity

Immunogen: An amino acid sequence from the C-terminus of human TNF Receptor-Associated Factor 4 (PKFISHQDIRKRNYVRDD) was used as the immunogen for this TRAF4 antibody (100% homologous in human, mouse and rat).

Isotype: IgG

Application Details

Application Notes: The stated application concentrations are suggested starting amounts. Titration of the TRAF4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the TRAF4 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for TRAF4

Target: TRAF4 (TNF Receptor-Associated Factor 4 (TRAF4))

Alternative Name: TRAF4 (TRAF4 Products)

Synonyms: CART1 antibody, MLN62 antibody, RNF83 antibody, A530032M13Rik antibody, msp2 antibody, traf4 antibody, cart1 antibody, mln62 antibody, rnf83 antibody, traf-4 antibody, traf4l antibody, zgc:77418 antibody, TNF receptor associated factor 4 antibody, Tnf receptor associated factor 4 antibody, tnf receptor-associated factor 4b antibody, TNF receptor associated factor 4 L homeolog antibody, tnf receptor-associated factor 4a antibody, TRAF4 antibody, Traf4 antibody, traf4b antibody, traf4.L antibody, traf4a antibody

Background: TNF Receptor-Associated Factor 4, also called CART1 or MLN62, is a protein that in humans is encoded by the TRAF4 gene. It is a member of the TNF receptor associated factor(TRAF) family, a family of scaffold proteins. Tomasetto et al.(1995) identified genes that are overexpressed in breast cancer by differential screening of cDNAs from breast cancer-derived metastatic axillary lymph nodes. The TRAF4 cDNA, which they designated MLN62, was mapped to 17q11-q12 by radioisotopic in situ hybridization. To investigate the biologic function of TRAF4, Regnier et al.(2002) generated Traf4-deficient mice by gene disruption.

UniProt: Q9BUZ4