FES antibody (C-Term)

Catalog No. ABIN3030921

Product Details anti-FES Antibody

Target: FES (Feline Sarcoma Oncogene (FES))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FES antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Antigen affinity

Immunogen: An amino acid sequence from the C-terminus of human Feline sarcoma oncogene (STIYQELQSIRKRHR) was used as the immunogen for this FES antibody.

Isotype: IgG

Application Details

Application Notes: The stated application concentrations are suggested starting amounts. Titration of the FES antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the FES antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for FES

Target: FES (Feline Sarcoma Oncogene (FES))

Alternative Name: FES (FES Products)

Synonyms: FPS antibody, RGD1564385 antibody, AI586313 antibody, BB137047 antibody, c-fes antibody, FES antibody, c-fps antibody, FES proto-oncogene, tyrosine kinase antibody, feline sarcoma oncogene antibody, FES antibody, Fes antibody, fes antibody

Background: Feline sarcoma oncogene is an enzyme that in humans is encoded by the FES gene. This gene encodes the human cellular counterpart of a feline sarcoma retrovirus protein with transforming capabilities. Non-onc intervening sequences were present in the human counterpart. The gene product has tyrosine-specific protein kinase activity and that activity is required for maintenance of cellular transformation. Its chromosomal location has linked it to a specific translocation event identified in patients with acute promyelocytic leukemia, but it is also involved in normal hematopoiesis. A truncated transcript has been identified that is generated utilizing a start site in one of the far downstream exons but a protein product associated with this transcript has not been identified.

UniProt: P07332

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Signaling Events mediated by VEGFR1 and VEGFR2