FGF2 antibody (AA 143-288)

Catalog No. ABIN3030934

This Rabbit Polyclonal antibody specifically detects FGF2 in WB, IHC (p) and ELISA (Standard). It exhibits reactivity toward Human.

Quick Overview for FGF2 antibody (AA 143-288) (ABIN3030934)

Target: FGF2 (Fibroblast Growth Factor 2 (Basic) (FGF2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FGF2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA (Standard)

Product Details anti-FGF2 Antibody

Binding Specificity: AA 143-288

Purification: Antigen affinity

Immunogen: Human partial recombinant protein (AA 143-288) was used as the immunogen for this FGF2 antibody.

Isotype: IgG

Application Details

Application Notes: The stated application concentrations are suggested starting amounts. Titration of the FGF2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot (recombinant protein): 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,ELISA: 0.1-0.5 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the FGF2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for FGF2

Target: FGF2 (Fibroblast Growth Factor 2 (Basic) (FGF2))

Alternative Name: FGF2

Background: FGF2 has been implicated in a multitude of physiologic and pathologic processes, including limb development, angiogenesis, wound healing, and tumor growth. Human FGF2 shares 96 % and 97 % amino acid sequence homology with mouse and rat respectively. It belongs to the fibroblast growth factor (FGF) family. FGFs exhibit widespread mitogenic and neurotrophic activities. Nine members of the family are currently known, and FGF1 and -2 are present in relatively high levels in CNS. FGF2 is expressed at low levels in many tissues and cell types and reaches high concentrations in brain and pituitary.

UniProt: P09038

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, C21-Steroid Hormone Metabolic Process, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Protein targeting to Nucleus, S100 Proteins