FOXM1 antibody (AA 411-763)

Catalog No. ABIN3030988

Product Details anti-FOXM1 Antibody

Target: FOXM1 (Forkhead Box M1 (FOXM1))

Binding Specificity: AA 411-763

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FOXM1 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Antigen affinity

Immunogen: Human partial recombinant protein (AA 411-763) was used as the immunogen for this FOXM1 antibody.

Isotype: IgG

Application Details

Application Notes: The stated application concentrations are suggested starting amounts. Titration of the FOXM1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the FOXM1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for FOXM1

Target: FOXM1 (Forkhead Box M1 (FOXM1))

Alternative Name: FOXM1 (FOXM1 Products)

Synonyms: FKHL16 antibody, FOXM1B antibody, HFH-11 antibody, HFH11 antibody, HNF-3 antibody, INS-1 antibody, MPHOSPH2 antibody, MPP-2 antibody, MPP2 antibody, PIG29 antibody, TGT3 antibody, TRIDENT antibody, FOXM1 antibody, AA408308 antibody, AW554517 antibody, BB238854 antibody, Fkh16 antibody, Foxm1b antibody, HFH-11B antibody, Mpm2 antibody, WIN antibody, Trident antibody, fkhl16 antibody, foxm1l antibody, hfh-11 antibody, mpp2 antibody, zgc:63854 antibody, forkhead box M1 antibody, forkhead box M1 S homeolog antibody, FOXM1 antibody, Foxm1 antibody, foxm1 antibody, foxm1.S antibody

Background: Forkhead box protein M1 is encoded by the FOXM1 gene. It is a member of the FOX family of transcription factors. FOXM1 is known to play a key role in cell cycle progression where endogenous FOXM1 expression peaks at S and G2/M phases and also in the control of cell proliferation. The gene is now known as a human proto-oncogene. Abnormal upregulation of the protein is involved in the oncogenesis of basal cell carcinoma, the most common human cancer worldwide. It is hypothesized that FOXM1 induces cancer initiation through stem/progenitor cell expansion. Additionally, FOXM1 has been shown to modulate the epigenome. It was found that overexpression of the protein brain washes normal cells to adopt cancer-like epigenome.

Gene ID: 2305

Pathways: Positive Regulation of Response to DNA Damage Stimulus