IL23A antibody (N-Term)

Catalog No. ABIN3031472

Product Details anti-IL23A Antibody

Target: IL23A (Interleukin 23, alpha subunit p19 (IL23A))

Binding Specificity: N-Term

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL23A antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Antigen affinity

Immunogen: An amino acid sequence from the N-terminus of mouse IL23 p19 (DWAQCQQLSRNLCMLAWNAH) was used as the immunogen for this IL23 p19 antibody.

Isotype: IgG

Application Details

Application Notes: The stated application concentrations are suggested starting amounts. Titration of the IL23 p19 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the IL23 p19 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for IL23A

Target: IL23A (Interleukin 23, alpha subunit p19 (IL23A))

Alternative Name: IL23 p19 (IL23A Products)

Synonyms: IL-23 antibody, IL-23A antibody, IL23P19 antibody, P19 antibody, SGRF antibody, FIL1 antibody, FIL1(ZETA) antibody, FIL1Z antibody, IL-1F7 antibody, IL-1H antibody, IL-1H4 antibody, IL-1RP1 antibody, IL-37 antibody, IL1F7 antibody, IL1H4 antibody, IL1RP1 antibody, p19 antibody, il23p19 antibody, IL23 antibody, interleukin 23 subunit alpha antibody, interleukin 37 antibody, interleukin 23, alpha subunit p19 antibody, IL23A antibody, IL37 antibody, Il23a antibody

Background: Interleukin-23 is a heterodimeric cytokine consisting of two subunits, one called p40, which is shared with another cytokine, IL-12, and another called p19 (the IL-23 alpha subunit). The International Radiation Hybrid Mapping Consortium mapped the IL-23 gene to chromosome 12. The cytokine is an important part of the inflammatory response against infection. It promotes upregulation of the matrix metalloprotease MMP9, increases angiogenesis and reduces CD8+ T-cell infiltration.

UniProt: Q9EQ14

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation