The stated application concentrations are suggested starting points. Titration of the IRAK1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
For Research Use only
0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
After reconstitution, the IRAK1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Interleukin-1 receptor-associated kinase 1, is an enzyme that in humans is encoded by the IRAK1 gene. By radiation hybrid analysis, this gene is mapped to chromosome Xq28. Serine/threonine-protein kinases play a critical roles in initiating innate immune response against foreign pathogens. This gene is involved in Toll-like receptor (TLR) and IL-1R signaling pathways. It encodes one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. This gene is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B.