Integrin Alpha2b antibody (APC)

Catalog No. ABIN303530

The Mouse Monoclonal anti-Integrin Alpha2b antibody has been validated for FACS. It is suitable to detect Integrin Alpha2b in samples from Human.

Quick Overview for Integrin Alpha2b antibody (APC) (ABIN303530)

Target: Integrin Alpha2b (CD41)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Integrin Alpha2b antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Clone: MEM-06

Product Details anti-Integrin Alpha2b Antibody (APC)

Purification: Size-Exclusion Chromatography.

Immunogen: Leukocytes of patient suffering from LGL-type leukaemia

Isotype: IgG1

Application Details

Application Notes: Flow Cytometry analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: Phosphate buffered saline (PBS) containing 15 mM Sodium Azide as preservative and 0.2 % (w/v) high-grade BSA (Protease free) as a stabilizing agent.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store the antibody at 2 - 8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light.
Shelf Life: one year from despatch.

Expiry Date: 12 months

Target Details for Integrin Alpha2b

Target: Integrin Alpha2b (CD41)

Alternative Name: CD41 / ITGA2B

Background: CD41 (platelet glycoprotein IIb) is composed of two subunits (120 kDa a, a and 23 kDa b, b) that interact with CD61 in the presence of calcium to form a functional adhesive protein receptor. Upon blood vessel damage, this receptor binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin. CD41 is mainly expressed on megakaryocyte-platelet lineage, but generally belongs to the antigens that are expressed during early stages of hematopoietic differentiation.Synonyms: GP2B, GPalpha IIb, ITGAB, Integrin alpha-IIb, Platelet membrane glycoprotein IIb

UniProt: P08514

Pathways: Integrin Complex