Integrin Alpha2b antibody (Biotin)

Catalog No. ABIN303531

The Biotin-conjugated Mouse Monoclonal anti-Integrin Alpha2b antibody (Clone MEM-06) (ABIN303531) specifically detects Integrin Alpha2b in FACS. The antibody is reactive with Human samples.

Quick Overview for Integrin Alpha2b antibody (Biotin) (ABIN303531)

Target: Integrin Alpha2b (CD41)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Integrin Alpha2b antibody is conjugated to Biotin

Application: Flow Cytometry (FACS)

Clone: MEM-06

Product Details anti-Integrin Alpha2b Antibody (Biotin)

Immunogen: Leukocytes of patient suffering from LGL-type leukaemia

Isotype: IgG1

Application Details

Application Notes: Indirect immunofluorescence analysis by Flow Cytometry: 1:200 as starting dilution.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antiboy at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezineg and thawing.
Shelf Life: one year from despatch.

Expiry Date: 12 months

Target Details for Integrin Alpha2b

Target: Integrin Alpha2b (CD41)

Alternative Name: CD41 / ITGA2B

Background: CD41 (platelet glycoprotein IIb) is composed of two subunits (120 kDa a, a and 23 kDa b, b) that interact with CD61 in the presence of calcium to form a functional adhesive protein receptor. Upon blood vessel damage, this receptor binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin. CD41 is mainly expressed on megakaryocyte-platelet lineage, but generally belongs to the antigens that are expressed during early stages of hematopoietic differentiation.Synonyms: GP2B, GPalpha IIb, ITGAB, Integrin alpha-IIb, Platelet membrane glycoprotein IIb

UniProt: P08514

Pathways: Integrin Complex