The Mouse Monoclonal anti-Integrin Alpha2b antibody (ABIN3037269) specifically detects Integrin Alpha2b in FACS, ELISA and IP.
The antibody is reactive with Cow samples.
The antibody IVA30 reacts with CD41/CD61 complex (bovine), one of the earliest markers of the megakaryocytic lineage. CD41/CD61 complex acts as the receptor for fibrinogen, fibronectin, Von Willebrand factor, vitronectin, thrombin and mediates platelets aggregation. CD41/CD61 is expressed only by platelets and megakaryocytes, the complex may be absent or strongly reduced in Glanzmann's thrombasthenia (GT).
Purification
Purified from ascites by protein-A affinity chromatography