LOX antibody (Middle Region)

Catalog No. ABIN3042506

The Rabbit Polyclonal anti-LOX antibody is suitable to detect LOX in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for LOX antibody (Middle Region) (ABIN3042506)

Target: LOX (Lysyl Oxidase (LOX))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LOX antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-LOX Antibody

Binding Specificity: Middle Region

Purpose: Anti-LOX Antibody

Sequence: AEENCLASTA YRADVRDYDH RVLLRFPQR

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: different from the related mouse,rat sequences by one amino acid.

Characteristics: Anti-LOX Antibody. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human LOX, different from the related mouse and rat sequences by one amino acid.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL, Mouse, Rat ELISA, 0.1-0.5 μg/mL, -

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for LOX

Target: LOX (Lysyl Oxidase (LOX))

Alternative Name: LOX

Background:

Background: Lysyl oxidase  (LOX), also known as protein-lysine 6-oxidase, is a protein that, in humans, is encoded by the LOX gene. The protein encoded by this gene is an extracellular copper enzyme that initiates the crosslinking of collagens and elastin. The enzyme catalyzes oxidative deamination of the epsilon-amino group in certain lysine and hydroxylysine residues of collagens and lysine residues of elastin. In addition to crosslinking extracellular matrix proteins, the encoded protein may have a role in tumor suppression. Defects in this gene are a cause of autosomal recessive cutis laxa type I (CL type I). Two transcript variants encoding different isoforms have been found for this gene. 

Gene Full Name: lysyl oxidase

Molecular Weight: 31 kDa

Gene ID: 4015

UniProt: P28300

Pathways: SARS-CoV-2 Protein Interactome