DRD5 antibody (C-Term)

Catalog No. ABIN3042836

Product Details anti-DRD5 Antibody

Target: DRD5 (Dopamine Receptor D5 (DRD5))

Binding Specificity: AA 388-407, C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DRD5 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for D(1B) dopamine receptor(DRD5) detection. Tested with WB in Human,Mouse,Rat.

Sequence: LISYNQDTVF HREIAAAYVH

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for D(1B) dopamine receptor(DRD5) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: dopamine receptor D5
Protein Name: D(1B) dopamine receptor

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of mouse Dopamine Receptor D5(388-407aa LISYNQDTVFHREIAAAYVH), different from the related rat sequence by two amino acids, and from the related human sequence by three amino acids.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Preservative: Thimerosal (Merthiolate), Sodium azide

Precaution of Use: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for DRD5

Target: DRD5 (Dopamine Receptor D5 (DRD5))

Alternative Name: DRD5 (DRD5 Products)

Synonyms: DRD5 antibody, DBDR antibody, DRD1B antibody, DRD1L2 antibody, D1B antibody, D5R antibody, Drd-5 antibody, Drd1b antibody, Gpcr1 antibody, dopamine receptor D5 antibody, DRD5 antibody, Drd5 antibody

Background: D(1B) dopamine receptor(DRD5), also called DRD1B or DRD1L2 is a protein that in humans is encoded by the DRD5 gene. This gene is mapped to 4p16.1. This gene encodes the D5 subtype of the dopamine receptor. The D5 subtype is a G-protein coupled receptor which stimulates adenylyl cyclase. This receptor is expressed in neurons in the limbic regions of the brain. It has a 10-fold higher affinity for dopamine than the D1 subtype. Pseudogenes related to this gene reside on chromosomes 1 and 2. Compared with DRD1, DRD5 displayed a higher affinity for dopamine and was able to stimulate a biphasic rather than a monophasic intracellular accumulation of cAMP.

Synonyms: D(1B) dopamine receptor antibody|D(5) dopamine receptor antibody|D1 beta dopamine receptor antibody|D1B dopamine receptor antibody|D1beta dopamine receptor antibody|D5 dopamine receptor antibody|DBDR antibody|Dopamine D5 receptor antibody|Dopamine receptor D1B antibody|DRD 1B antibody|DRD 5 antibody|DRD1B antibody|DRD1L2 antibody|DRD5 antibody|DRD5_HUMAN antibody|MGC10601 antibody

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones, cAMP Metabolic Process, Regulation of long-term Neuronal Synaptic Plasticity