SERPINA4 antibody (C-Term)

Catalog No. ABIN3043135

Product Details anti-SERPINA4 Antibody

Target: SERPINA4 (serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 4 (SERPINA4))

Binding Specificity: AA 384-401, C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SERPINA4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Rabbit IgG polyclonal antibody for Kallistatin(SERPINA4) detection. Tested with WB, IHC-P in Human.

Sequence: AIKFFSAQTN RHILRFNR

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Kallistatin(SERPINA4) detection. Tested with WB, IHC-P in Human.
Gene Name: serpin peptidase inhibitor, clade A(alpha-1 antiproteinase, antitrypsin), member 4
Protein Name: Kallistatin

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Kallistatin(384-401aa AIKFFSAQTNRHILRFNR).

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Preservative: Thimerosal (Merthiolate), Sodium azide

Precaution of Use: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for SERPINA4

Target: SERPINA4 (serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 4 (SERPINA4))

Alternative Name: SERPINA4 (SERPINA4 Products)

Synonyms: KLKR antibody, Klk6 antibody, hK1 antibody, KAL antibody, KLST antibody, KST antibody, PI-4 antibody, PI4 antibody, kallistatin antibody, SERPINA4 antibody, DKFZp469E1737 antibody, KALps antibody, Klst antibody, kallikrein 1 antibody, serpin family A member 4 antibody, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 antibody, serine (or cysteine) peptidase inhibitor, clade A, member 4, pseudogene 1 antibody, KLK1 antibody, SERPINA4 antibody, Serpina4 antibody, SPIA4 antibody, Serpina4-ps1 antibody

Background: Serpina 4, also called Kallistatin, PI4 or TISSUE KALLIKREIN INHIBITOR, is a protein that in humans is encoded by the SERPINA4 gene. The serpina4 is a member of the serpin superfamily and represents a major inhibitor of human tissue kallikrein in the circulation. The SERPINA4 gene is localized to 14q32.13. The translated amino acid sequence of serpina4 matches the protein sequence and shares 44 to 46 % sequence identity with other serpin family members. Kallistatin is a serine proteinase inhibitor(serpin) and a heparin-binding protein. It is localized in vascular smooth muscle cells and endothelial cells of blood vessels, suggesting that it may be involved in the regulation of vascular function. And serpina4 also plays a role in neointima hyperplasia.

Synonyms: KAIN_HUMAN antibody|KAL antibody|Kallikrein binding protein antibody|Kallikrein inhibitor antibody|Kallistatin antibody|KBP antibody|KLST antibody|KST antibody|MGC108582 antibody|Peptidase inhibitor 4 antibody|PI-4 antibody|PI4 antibody|Protease inhibitor 4(kallistatin) antibody|Protease inhibitor 4 antibody|Serine(or cysteine) proteinase inhibitor, clade A(alpha 1 antiproteinase, antitrypsin), member 4 antibody|Serpin A4 antibody|Serpin peptidase inhibitor clade A member 4 antibody|Serpin peptidase inhibitor, clade A(alpha 1 antiproteinase, antitrypsin), member 4 antibody|SERPINA4 antibody

UniProt: P29622