TFF1 antibody (AA 25-84)

Catalog No. ABIN3043309

Product Details anti-TFF1 Antibody

Target: TFF1 (Trefoil Factor 1 (TFF1))

Binding Specificity: AA 25-84

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TFF1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purpose: Rabbit IgG polyclonal antibody for Trefoil factor 1(TFF1) detection. Tested with WB, ELISA in Human.

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Trefoil factor 1(TFF1) detection. Tested with WB, ELISA in Human.
Gene Name: trefoil factor 1
Protein Name: Trefoil factor 1

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human TFF1 recombinant protein (Position: E25-F84). Human TFF1 shares 66.7% and 69% amino acid (aa) sequence identity with mouse and rat TFF1, respectively.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
ELISA: Concentration: 0.1-0.5 μg/mL, Tested Species: Human

Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for TFF1

Target: TFF1 (Trefoil Factor 1 (TFF1))

Alternative Name: TFF1 (TFF1 Products)

Synonyms: BCEI antibody, D21S21 antibody, HP1.A antibody, HPS2 antibody, pNR-2 antibody, pS2 antibody, Bcei antibody, PS2 antibody, bcei antibody, d21s21 antibody, hp1.a antibody, hps2 antibody, p1 antibody, p1-a antibody, pnr-2 antibody, ps2 antibody, tff1 antibody, xP1 antibody, xp1-L antibody, xp1 antibody, TFF1 antibody, Ps2 antibody, trefoil factor 1 antibody, trefoil factor 1 S homeolog antibody, trefoil factor 1, gene 2 S homeolog antibody, TFF1 antibody, Tff1 antibody, tff1.S antibody, tff1.2.S antibody, LOC100358238 antibody

Background: TFF1 (Trefoil factor 1), also known as pS2, is a protein that in humans is encoded by the TFF1 gene. Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer, and affect healing of the epithelium. It is found that TFF1 in normal human urine inhibited the growth of calcium oxalate crystals. Urinary TFF1 showed an inhibitory potency similar to that of nephrocalcin, and inhibition was dose dependent and inhibited by TFF1 antisera, particularly by antisera directed to the TFF1 C terminus. Concentrations and relative amounts of TFF1 in the urine of patients with idiopathic calcium oxalate kidney stones were significantly less than those found in controls. This gene, which is expressed in the gastric mucosa, has also been studied because of its expression in human tumors. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21.

Synonyms: BCEI antibody|Breast cancer estrogen inducible protein antibody|Breast cancer estrogen inducible sequence antibody|Breast cancer estrogen-inducible protein antibody|D21S21 antibody|Gastrointestinal trefoil protein antibody|Gastrointestinal trefoil protein pS2 antibody|hP1.A antibody|HP1A antibody|HPS 2 antibody|HPS2 antibody|pNR 2 antibody|PNR-2 antibody|pNR2 antibody|Polypeptide P1.A antibody|Protein pS2 antibody|PS 2 antibody|pS2 antibody|pS2 protein antibody|TFF 1 antibody|TFF1 antibody|TFF1_HUMAN antibody|Trefoil factor 1 antibody

Gene ID: 7031

UniProt: P04155

Pathways: EGFR Signaling Pathway