CD79a antibody (AA 121-226)

Catalog No. ABIN3043397

Product Details anti-CD79a Antibody

Target: CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))

Binding Specificity: AA 121-226

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CD79a antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Purpose: Rabbit IgG polyclonal antibody for B-cell antigen receptor complex-associated protein alpha chain(CD79A) detection. Tested with WB, IHC-P, ICC in Human,Rat.

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for B-cell antigen receptor complex-associated protein alpha chain(CD79A) detection. Tested with WB, IHC-P, ICC in Human,Rat.
Gene Name: CD79a molecule, immunoglobulin-associated alpha
Protein Name: B-cell antigen receptor complex-associated protein alpha chain

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human CD79a recombinant protein (Position: T121-P226). Human CD79a shares 91% amino acid (aa) sequence identity with mouse CD79a.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
IHC-F: Concentration: 0.5-1 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and ICC.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for CD79a

Target: CD79a (CD79A) (B-cell antigen receptor complex-associated protein alpha chain (CD79A))

Alternative Name: CD79A (CD79A Products)

Synonyms: CD79A antibody, Ig-alpha antibody, Iga antibody, Igalpha antibody, Ly-54 antibody, Ly54 antibody, mb-1 antibody, IGA antibody, MB-1 antibody, IG-alpha antibody, CD79a molecule antibody, CD79A antigen (immunoglobulin-associated alpha) antibody, Cd79a molecule-like antibody, CD79A antibody, Cd79a antibody, Cd79al antibody

Background: Cluster of differentiation CD79A also known as B-cell antigen receptor complex-associated protein alpha chain and MB-1 membrane glycoprotein, is a protein that in humans is encoded by the CD79A gene. It is mapped to 19q13.2. CD79A is a membrane protein with an extracellular immunoglobulin domain, a single span transmembrane region and a short cytoplasmic domain. Genetic deletion of the transmembrane exon of CD79A results in loss of CD79A protein and a complete block of B cell development at the pro to pre B cell transition. Similarly, humans with homozygous splice variants in CD79A predicted to result in loss of the transmembrane region and a truncated or absent protein display agammaglobulinemia and no peripheral B cells.

Synonyms: B cell antigen receptor complex associated protein alpha chain antibody|B cell antigen receptor complex associated protein alpha chain precursor antibody|B Lymphocyte Specific MB1 Protein antibody|B lymphocyte-specific MB1 protein antibody|B-cell antigen receptor complex-associated protein alpha chain antibody|CD 79a antibody|CD79a antibody|CD79a antigen (immunoglobulin-associated alpha) antibody|CD79A antigen antibody|CD79A antigen immunoglobulin associated alpha antibody|CD79a molecule immunoglobulin associated alpha antibody|CD79a molecule, immunoglobulin-associated alpha antibody|CD79A_HUMAN antibody|Ig alpha antibody|Ig-alpha antibody|IGA antibody|IgM-alpha antibody|Immunoglobulin Associated Alpha antibody|Immunoglobulin-associated alpha antibody|Ly54 antibody|MB 1 antibody|MB 1 membrane glycoprotein antibody|MB-1 membrane glycoprotein antibody|MB1 antibody|MB1 membrane glycoprotein antibody|Membrane bound immunoglobulin associated protein antibody|Membrane-bound immunoglobulin-associated protein antibody|Surface IgM associated protein antibody|Surface IgM-associated protein antibody

Gene ID: 973

UniProt: P11912

Pathways: BCR Signaling