NRIP1 antibody (N-Term)

Catalog No. ABIN3043581

Product Details anti-NRIP1 Antibody

Target: NRIP1 (Nuclear Receptor Interacting Protein 1 (NRIP1))

Binding Specificity: AA 273-306, N-Term

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NRIP1 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for Nuclear receptor-interacting protein 1(NRIP1) detection. Tested with WB in Human,Mouse,Rat.

Sequence: EAHLQQYSRE HALKTQNANQ AASERLAAMA RLQE

Cross-Reactivity (Details): Predicted Cross Reactivity: human
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Characteristics: Rabbit IgG polyclonal antibody for Nuclear receptor-interacting protein 1(NRIP1) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: nuclear receptor interacting protein 1
Protein Name: Nuclear receptor-interacting protein 1

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human RIP140 (273-306aa EAHLQQYSREHALKTQNANQAASERLAAMARLQE), different from the related mouse sequence by two amino acids.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse, Rat, Predicted Species: Human
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for NRIP1

Target: NRIP1 (Nuclear Receptor Interacting Protein 1 (NRIP1))

Alternative Name: NRIP1 (NRIP1 Products)

Synonyms: MGC68665 antibody, NRIP1 antibody, RIP140 antibody, 6030458L20Rik antibody, 8430438I05Rik antibody, 9630050P12 antibody, AA959574 antibody, AW456757 antibody, nuclear receptor interacting protein 1 S homeolog antibody, nuclear receptor interacting protein 1 antibody, circumsporozoite protein antibody, nrip1.S antibody, NRIP1 antibody, nrip1 antibody, Nrip1 antibody, LOC100627733 antibody

Background: Nuclear receptor-interacting protein 1 (NRIP1), also known as receptor-interacting protein 140 (RIP140), is a protein that in humans is encoded by the NRIP1 gene. It is a nuclear protein that specifically interacts with the hormone-dependent activation domain AF2 of nuclear receptors. Also known as RIP140, this protein is a key regulator which modulates transcriptional activity of a variety of transcription factors, including the estrogen receptor. RIP140 has an important role in regulating lipid and glucose metabolism, and regulates gene expression in metabolic tissues including heart, skeletal muscle, and liver. A major role for RIP140 in adipose tissue is to block the expression of genes involved in energy dissipation and mitochondrial uncoupling, including uncoupling protein 1 and carnitine palmitoyltransferase 1b.

Synonyms: NRIP 1 antibody|NRIP1 antibody|NRIP1_HUMAN antibody|Nuclear factor RIP 140 antibody|Nuclear factor RIP140 antibody|Nuclear receptor interacting protein 1 antibody|Nuclear receptor-interacting protein 1 antibody|Receptor interacting protein 140 antibody|Receptor-interacting protein 140 antibody|RIP 140 antibody|RIP140 antibody

Gene ID: 8204

UniProt: P48552

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway