ERBB3 antibody (AA 1330-1342)
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- Target See all ERBB3 Antibodies
- ERBB3 (Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3))
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Binding Specificity
- AA 1330-1342
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Reactivity
- Human, Rat, Monkey, Horse, Pig, Bat, Hamster
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Host
- Goat
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Clonality
- Polyclonal
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Conjugate
- This ERBB3 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Brand
- IHC-plus™
- Specificity
- Human ERBB3. This antibody is expected to recognise isoform 1 (NP_001973.2) only.
- Predicted Reactivity
- Percent identity by BLAST analysis: Human, Orangutan, Gibbon, Monkey, Marmoset, Rat, Bat, Hamster, Panda, Horse, Pig (100%) Mouse, Bovine (92%).
- Purification
- Immunoaffinity purified
- Immunogen
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Synthetic peptide C-HSRLFPKANAQRT from the C-terminus of human ERBB3 (NP_001973.2). Percent identity by BLAST analysis: Human, Orangutan, Gibbon, Monkey, Marmoset, Rat, Bat, Hamster, Panda, Horse, Pig (100%), Mouse, Bovine (92%).
Type of Immunogen: Synthetic peptide - Top Product
- Discover our top product ERBB3 Primary Antibody
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- Application Notes
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Approved: IHC, IHC-P (5 μg/mL), Peptide-ELISA (1:32000), WB (0.1 - 0.3 μg/mL)
Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 5 μg/mL. - Comment
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Target Species of Antibody: Human
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Tris-buffered saline, pH 7.3, 0.5 % BSA, 0.02 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Minimize freezing and thawing.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze-thaw cycles.
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- Target
- ERBB3 (Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3))
- Alternative Name
- HER3 / ERBB3 (ERBB3 Products)
- Synonyms
- ErbB-3 antibody, HER3 antibody, LCCS2 antibody, MDA-BF-1 antibody, c-erbB-3 antibody, c-erbB3 antibody, erbB3-S antibody, p180-ErbB3 antibody, p45-sErbB3 antibody, p85-sErbB3 antibody, ERBB3 antibody, C76256 antibody, Erbb-3 antibody, Erbb3r antibody, Her3 antibody, nuc-ErbB3 antibody, erb-b2 receptor tyrosine kinase 3 antibody, v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) antibody, ERBB3 antibody, Erbb3 antibody
- Background
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Name/Gene ID: ERBB3
Subfamily: EGF Receptor
Family: Protein Kinase
Synonyms: ERBB3, C-erbB-3, C-erbB3, ErbB-3, HER3, p85-sErbB3, p45-sErbB3, MDA-BF-1, ErbB3-S, LCCS2, p180-ErbB3 - Gene ID
- 2065
- NCBI Accession
- NP_001973
- UniProt
- P21860
- Pathways
- RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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