CD46 antibody (PE)

Catalog No. ABIN306172

This Mouse Monoclonal antibody specifically detects CD46 in WB, FACS, IHC, IP and IHC (p). It exhibits reactivity toward Human.

Quick Overview for CD46 antibody (PE) (ABIN306172)

Target: CD46

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD46 antibody is conjugated to PE

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: MEM-258

Product Details anti-CD46 Antibody (PE)

Specificity: Recognizes the human CD46 cell surface antigen, a broadly expressed glycoprotein also known as membrane co-factor protein (MCP). CD46 functions as an inhibitor of complement activation limiting the formation and activity of C3 convertases. CD46 is expressed by all nucleated cells, often as multiple isoforms on the same cells. The molecule is also expressed by sperm and may be important in the process of fertilization.

Purification: Protein A purified

Immunogen: HPB-ALL cell line.

Type of Immunogen: Cells

Isotype: IgG1

Application Details

Application Notes: Approved: Flo (1:1), IHC, IHC-P, IP, WB

Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 or 100 μL whole blood. Method sheets are available on request.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute in 1 mL distilled water.

Concentration: Lot specific

Buffer: Lyophilized, PBS, 0.09 % sodium azide, 1 % BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze! Sensitive to light.

Storage: 4 °C

Storage Comment: May be stored at 4°C before opening. DO NOT FREEZE! Stable at 4°C as an undiluted liquid. Stable for at least 1 year. Protect from light.

Target Details for CD46

Target: CD46

Alternative Name: MCP / CD46

Background: Name/Gene ID: CD46

Synonyms: CD46, AHUS2, CD46 antigen, MCP, Measles virus receptor, TLX, MIC10, TRA2.10, Membrane cofactor protein

Gene ID: 4179

UniProt: P15529

Pathways: Regulation of Actin Filament Polymerization