Bcl-2 antibody

Catalog No. ABIN306549

The Sheep Polyclonal anti-Bcl-2 antibody (ABIN306549) specifically detects Bcl-2. The antibody is reactive with Human, Rat and Dog samples.

Quick Overview for Bcl-2 antibody (ABIN306549)

Target: Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))

Reactivity: Human, Rat, Dog

Host: Sheep

Clonality: Polyclonal

Conjugate: This Bcl-2 antibody is un-conjugated

Application: Please inquire

Product Details anti-Bcl-2 Antibody

Isotype: IgG

Application Details

Restrictions: For Research Use only

Handling

Target Details for Bcl-2

Target: Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))

Alternative Name: bcl-2

Background: Human hematopoetic malignancies are often characterized by gene rearrangements that deregulate gene expression. Antibodies to human bcl-2 (B cell leukemia/lymphoma 2) are directed against the gene isolated at the chromosomal breakpoint t(14,18) Bcl-2 which suppress programmed cell death (apoptosis) and appears to be modulated by association with bax, a cell death promoter. Synonyms: hbcl2, sheep anti human bcl 2, bcl-2.

UniProt: P10415

Pathways: MAPK Signaling, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagy, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling