Cyclin D1 antibody

Catalog No. ABIN306565

This Mouse Monoclonal antibody specifically detects Cyclin D1 in WB, IHC and IP. It exhibits reactivity toward Human, Mouse, Rat and Orang-Utan.

Quick Overview for Cyclin D1 antibody (ABIN306565)

Target: Cyclin D1 (CCND1)

Reactivity: Human, Mouse, Rat, Orang-Utan

Host: Mouse

Clonality: Monoclonal

Conjugate: This Cyclin D1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Clone: DCS-6

Product Details anti-Cyclin D1 Antibody

Purpose: Mouse anti Human Cyclin D1

Characteristics: The immunogen for the anti-human Cyclin D1 was a recombinant Cyclin Dd1 protein. This antibody recognizes a protein of 36kD and is a key cell cycle regulator and a putative protooncogene overexpressed in a wide variety of human neoplasms. DCS6 neutralizes the activity of Cyclin D1 in vivo.

Purification: Protein A/G Chromatography

Immunogen: A recombinant Cyclin Dd1 protein

Isotype: IgG2a

Application Details

Application Notes: Applications: Western Blot, Immunohistochemistry, Immunoprecipitation.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: phosphate buffered saline with 0.08 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Target Details for Cyclin D1

Target: Cyclin D1 (CCND1)

Alternative Name: Cyclin D1

Background: G1/S-specific Cyclin D1, CCND1

UniProt: P24385, P25322, P39948, Q5R6J5

Pathways: PI3K-Akt Signaling, Cell Division Cycle, Mitotic G1-G1/S Phases, ER-Nucleus Signaling