CAPNL1 antibody

Catalog No. ABIN306693

The Mouse Monoclonal anti-CAPNL1 antibody (Clone 15C10) (ABIN306693) specifically detects CAPNL1 in WB, IP and EIA. The antibody is reactive with Human, Mouse, Rat and Cow samples.

Quick Overview for CAPNL1 antibody (ABIN306693)

Target: CAPNL1 (Calpain 1, Large Subunit (CAPNL1))

Reactivity: Human, Mouse, Rat, Cow

Host: Mouse

Clonality: Monoclonal

Conjugate: This CAPNL1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Enzyme Immunoassay (EIA)

Clone: 15C10

Product Details anti-CAPNL1 Antibody

Purpose: Mouse anti Human Calpain I (large subunit, p80)

Cross-Reactivity: Cow, Human, Mouse, Rat

Characteristics: The calpains are calcium-dependent cysteine proteases that are widely expressed in mammalian systems. Both m-calpain (calpain II) and μ-calpain (calpain I) are composed of an 80 kD subunit and a 30 kD subunit. Whereas the 30 kD subunit is shared by both enzymes, the larger catalytic subunits are different and exhibit the distinct Ca ++ requirements that are suggested by their names. Whereas m-calpain requires millimolar ( mM) levels of calcium, μ-calpain is active at micromolar (uM) concentrations of Ca ++. In addition to the ubiquitously expressed m- and μcalpains, some tissue-specific calpains have been identified. The calpains appear to serve multiple physiological roles, and ideas concerning the functions of these enzymes are in a state of rapid flux.

Purification: Protein A/G Chromatography

Isotype: IgG1

Application Details

Application Notes: Use at 0.5-1 μg/mL for ELISA and Western blot, 1-2 μg/mL for immunoprecipitation.

Restrictions: For Research Use only

Handling

Storage: -20 °C

Storage Comment: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Target Details for CAPNL1

Target: CAPNL1 (Calpain 1, Large Subunit (CAPNL1))

Background: Mouse Anti-Calpain I, u-Calpain (Large subunit, p80), Monoclonal Antibody

UniProt: P07384

Pathways: Apoptosis