CD55 antibody

Catalog No. ABIN3071829

Product Details anti-CD55 Antibody

Target: CD55 (Complement Decay-Accelerating Factor (CD55))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD55 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Characteristics: The clone F4-29D9 binds with a single chain 70 kDa glycoprotein and identified as CD55 (also known as decay accelerating factor, DAF). CD55 is widely expressed on cells throughout the body including leukocytes, erythrocytes, epithelium, endothelium, and fibroblasts. It is a Glycosyl phosphatidylinositol anchored (GPI-anchored) protein and inhibits autologous complement cascade activation. CD55 also serves as receptor for CD97, echovirus and Coxsackie B virus. Anticd55 is a useful marker for the diagnosis of paroxysmal nocturnal hemoglobinuria (PNH).

Purification: Purified

Purity: >95 %

Grade: GMP Grade

Immunogen: Human umbilical vein endothelial cells (HUVEC)

Clone: F4-29D9

Isotype: IgG1 kappa

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS pH 7.2, 0.1 % (w/v) BSA, 0.09 % (w/v) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Target Details for CD55

Target: CD55 (Complement Decay-Accelerating Factor (CD55))

Alternative Name: CD55 (CD55 Products)

Synonyms: CR antibody, CROM antibody, DAF antibody, TC antibody, Daf antibody, Daf-GPI antibody, Daf1 antibody, GPI-DAF antibody, CD55 molecule (Cromer blood group) antibody, CD55 molecule, decay accelerating factor for complement antibody, CD55 antibody, Cd55 antibody

Background: The clone F4-29D9 binds with a single chain 70 kDa glycoprotein and identified as CD55 (also known as decay accelerating factor, DAF). CD55 is widely expressed on cells throughout the body including leukocytes, erythrocytes, epithelium, endothelium, and fibroblasts. It is a Glycosyl phosphatidylinositol anchored (GPI-anchored) protein and inhibits autologous complement cascade activation. CD55 also serves as receptor for CD97, echovirus and Coxsackie B virus. Anticd55 is a useful marker for the diagnosis of paroxysmal nocturnal hemoglobinuria (PNH).

NCBI Accession: NP_000565, NM_000574, NP_001108224, NM_001114752, NP_001287832, NM_001300903, NP_001287833

UniProt: P08174

Pathways: Complement System, Regulation of Leukocyte Mediated Immunity