CD11b antibody

Catalog No. ABIN308113

This Rat Monoclonal antibody specifically detects CD11b in FACS, IHC, WB, IP, Func, IHC (p), BR and DB. It exhibits reactivity toward Mouse.

Quick Overview for CD11b antibody (ABIN308113)

Target: CD11b (ITGAM) (Integrin alpha M (ITGAM))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This CD11b antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC), Western Blotting (WB), Immunoprecipitation (IP), Functional Studies (Func), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Blocking Reagent (BR), Dot Blot (DB)

Clone: M1-70-15

Product Details anti-CD11b Antibody

Specificity: Anti-mouse CD11b (Mac-1, Ly 40) monoclonal antibody is specific for the 170 kD a subunit of Mac-1 which mediates adhesion to ICAM-1 (CD54) and C3bi. Mac-1 is expressed on granulocytes, macrophages, natural killer cells, and B-1 cells in the peritoneal an.

Immunogen:

Type of Immunogen: Native protein

Isotype: IgG2b

Application Details

Application Notes: Approved: Block, DB, Flo, Func, IHC, IHC-P, IP, WB

Usage: The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.

Comment:

Target Species of Antibody: Mouse

Restrictions: For Research Use only

Handling

Concentration: Lot specific

Preservative: Azide free

Target Details for CD11b

Target: CD11b (ITGAM) (Integrin alpha M (ITGAM))

Alternative Name: ITGAM / CD11b

Background: Name/Gene ID: ITGAM
Family: Integrin

Synonyms: ITGAM, Antigen CD11b (p170), CD11B, CD11b antigen, CR3A, Integrin alpha-M, MAC-1, MO1A, Neutrophil adherence receptor, MAC1A, SLEB6, CR-3 alpha chain

Gene ID: 3684

UniProt: P11215

Pathways: Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation