Complement Factor B antibody (Fragment Bb)

Catalog No. ABIN317054

The Mouse Monoclonal anti-Complement Factor B antibody is suitable to detect Complement Factor B in samples from Human. It has been validated for WB, FACS and EIA.

Quick Overview for Complement Factor B antibody (Fragment Bb) (ABIN317054)

Target: Complement Factor B (CFB)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Complement Factor B antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Clone: 032B-22-1-X

Product Details anti-Complement Factor B Antibody

Binding Specificity: Fragment Bb

Specificity: This antibody recognises a neoantigen of the Bb fragment of complement factor B.

Characteristics: Synonyms: Properdin factor B, C3/C5 convertase, PBF2, CFB, BF, BFD, Glycine-rich beta glycoprotein

Purification: Purified IgG prepared by affinity chromatography on Protein A

Immunogen: Binds neoantigen of fragment Bb from human complement factor B.

Isotype: IgG2a

Application Details

Application Notes: Flow Cytometry. ELISA. Western Blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0mg/mL

Buffer: Borate buffered saline pH 8.2 - 8.4 containing 0.02 % Sodium Azide (NaN3)

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. Caution: (A full Health and Safety assessment is available upon request) This product containsSodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled bytrained staff only.

Expiry Date: 12 months

Target Details for Complement Factor B

Target: Complement Factor B (CFB)

Alternative Name: Complement Factor B

Background: Factor B is present in blood serum. C3b associates with complement factor B, inducing conformational change. This enables complement factor D to cleave the N-terminal of complement factor B (the Ba subunit) leaving the 63 kDa Bb subunit associated with C3b and forming C3 convertase. Subunit Bb is involved in the proliferation of preactivated B lymphocytes. Conversely, Ba inhibits lymphocyte proliferation.Synonyms: BF, BFD, C3/C5 convertase, CFB, Glycine-rich beta glycoprotein, PBF2, Properdin factor B

Gene ID: 629

UniProt: P00751

Pathways: Complement System, Proton Transport, Ribonucleoside Biosynthetic Process