FADD antibody (Fas (TNFRSF6)-Associated Via Death Domain) (AA 1-208)

Details for Product anti-FADD Antibody No. ABIN317514
Antigen
Epitope
AA 1-208, N-Term
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Reactivity
Human
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9
1
Host
Mouse
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47
Clonality (Clone)
Monoclonal ()
Conjugate
This FADD antibody is un-conjugated
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Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
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Options
Immunogen Recombinant human FADD (1-208 aa) purified from E. coli
Clone J1D2
Isotype IgG2b
Specificity The antibody recognizes human FADD. Other species not tested.
Characteristics Synonyms: FAS-associated death domain protein, MORT1, GIG3, FAS-associating deathdomain-containing protein, Mediator of receptor induced toxicity, Growth-inhibiting gene 3protein
Purification Protein-G affinity chromatography
Antigen
Alternative Name FADD (FADD Antibody Abstract)
Background FADD (Fas-associated protein with death domain) is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. This protein is implicated in survival/proliferation and cell cycle progression. FADD functions are also regulated via cellular sublocalization, protein phosphorylation, and inhibitory molecules.Synonyms: FAS-associated death domain protein, FAS-associating death domain-containing protein, GIG3, Growth-inhibiting gene 3 protein, MORT1, Mediator of receptor induced toxicity
Gene ID 8772
UniProt Q13158
Pathways Apoptosis, TLR Signaling, Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades
Application Notes ELISA. Western blot (1: 500 - 1,000). Immunohistochemistry on paraffin sections (1: 50 - 1: 100).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 1.0 mg/mL
Buffer PBS, pH 7.4, containing 0.09 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Expiry Date 12 months
Supplier Images
Image no. 1 for anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) (AA 1-208), (N-Term) antibody (ABIN317514) anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) (AA 1-208), (N-Term) antibody (Image 1)
Image no. 2 for anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) (AA 1-208), (N-Term) antibody (ABIN317514) anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) (AA 1-208), (N-Term) antibody (Image 2)
Image no. 3 for anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) (AA 1-208), (N-Term) antibody (ABIN317514) anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) (AA 1-208), (N-Term) antibody (Image 3)
Image no. 4 for anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) (AA 1-208), (N-Term) antibody (ABIN317514) anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) (AA 1-208), (N-Term) antibody (Image 4)