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FADD antibody (N-Term)

FADD Reactivity: Human WB, IHC (p), EIA Host: Mouse Monoclonal J1D2 unconjugated
Catalog No. ABIN317515
  • Target See all FADD Antibodies
    FADD (Fas (TNFRSF6)-Associated Via Death Domain (FADD))
    Binding Specificity
    • 18
    • 15
    • 15
    • 8
    • 8
    • 7
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-208, N-Term
    Reactivity
    • 88
    • 61
    • 19
    • 18
    • 15
    Human
    Host
    • 98
    • 18
    Mouse
    Clonality
    • 94
    • 22
    Monoclonal
    Conjugate
    • 68
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This FADD antibody is un-conjugated
    Application
    • 90
    • 51
    • 31
    • 15
    • 15
    • 15
    • 12
    • 9
    • 6
    • 5
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificity
    The antibody recognizes human FADD. Other species not tested.
    Characteristics
    Synonyms: FAS-associated death domain protein, MORT1, GIG3, FAS-associating deathdomain-containing protein, Mediator of receptor induced toxicity, Growth-inhibiting gene 3protein
    Purification
    Protein-G affinity chromatography
    Immunogen
    Recombinant human FADD (1-208 aa) purified from E. coli
    Clone
    J1D2
    Isotype
    IgG2b
    Top Product
    Discover our top product FADD Primary Antibody
  • Application Notes
    ELISA. Western blot (1: 500 - 1,000). Immunohistochemistry on paraffin sections (1: 50 - 1: 100).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.0 mg/mL
    Buffer
    PBS, pH 7.4, containing 0.09 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.
    Expiry Date
    12 months
  • Target
    FADD (Fas (TNFRSF6)-Associated Via Death Domain (FADD))
    Alternative Name
    FADD (FADD Products)
    Synonyms
    MORT1 antibody, Mort1/FADD antibody, Mort1 antibody, TNFRSF6 antibody, adaptor antibody, fadd antibody, mort1 antibody, xfadd antibody, Fas associated via death domain antibody, Fas (TNFRSF6)-associated via death domain antibody, Fas associated via death domain S homeolog antibody, Fas (tnfrsf6)-associated via death domain antibody, FADD antibody, Fadd antibody, fadd.S antibody, fadd antibody
    Background
    FADD (Fas-associated protein with death domain) is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. This protein is implicated in survival/proliferation and cell cycle progression. FADD functions are also regulated via cellular sublocalization, protein phosphorylation, and inhibitory molecules.Synonyms: FAS-associated death domain protein, FAS-associating death domain-containing protein, GIG3, Growth-inhibiting gene 3 protein, MORT1, Mediator of receptor induced toxicity
    Gene ID
    8772
    UniProt
    Q13158
    Pathways
    Apoptosis, TLR Signaling, Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades
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