Cadherin 8 antibody
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- Target See all Cadherin 8 (CDH8) Antibodies
- Cadherin 8 (CDH8)
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Cadherin 8 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificity
- This antibody detects endogenous levels of Cadherin-8 protein.(region surrounding Ala519)
- Purification
- Affinity Chromatography using epitope-specific immunogen
- Top Product
- Discover our top product CDH8 Primary Antibody
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- Application Notes
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Western Blot: 1/500-1/1000. Immunohistochemistry: 1/50-1/200. Immunofluorescence: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH ~7.2, 15 mM Sodium Azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- Cadherin 8 (CDH8)
- Alternative Name
- Cadherin-8 (CDH8 Products)
- Synonyms
- AI851472 antibody, cad8 antibody, cadherin-8 antibody, Nbla04261 antibody, cadherin 8 antibody, cadherin 8, type 2 antibody, Cdh8 antibody, CDH8 antibody
- Background
- The cadherins are a family of Ca++-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. Cadherins each contain a large extracellular domain at the amino terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short carboxy terminal, intracellular domain interacts with a variety of cytoplasmic proteins, including beta-catenin, to regulate cadherin function. cadherin-8 expression has been seen in mouse thymus tissue as well as in specific subdivisions of the developing central nervous system. It plays a potential role in brain morphology.Synonyms: CDH8
- Molecular Weight
- approx. 70 kDa
- Gene ID
- 1006
- NCBI Accession
- NP_001787
- UniProt
- P55286
- Pathways
- Cell-Cell Junction Organization
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