p53 antibody (meLys370)

Catalog No. ABIN3181606

The Mouse Monoclonal anti-p53 antibody is suitable to detect p53 in samples from Human, Mouse and Rat. It has been validated for IHC.

Quick Overview for p53 antibody (meLys370) (ABIN3181606)

Target: p53 (TP53) (Tumor Protein P53 (TP53))

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This p53 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: Q59

Product Details anti-p53 Antibody

Binding Specificity: meLys370

Specificity: The antibody detects P53 (Mono Methyl Lys370)

Characteristics: Mouse Monoclonal to P53 (Mono Methyl Lys370).

Purification: The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthetic Peptide

Isotype: IgG1

Application Details

Application Notes: IHC 1:50-1:200

Comment:

Customer Validation 101267: antibody is not specific for p53meK370 in vitro and in cellulo (293T cells)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C.

Target Details for p53

Target: p53 (TP53) (Tumor Protein P53 (TP53))

Alternative Name: P53

Gene ID: 7157

UniProt: P04637

Pathways: p53 Signaling, MAPK Signaling, PI3K-Akt Signaling, Apoptosis, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagy, Warburg Effect