CHEK1 antibody (pSer345)

Catalog No. ABIN3181962

This Rabbit Polyclonal antibody specifically detects CHEK1 in ELISA and IHC. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for CHEK1 antibody (pSer345) (ABIN3181962)

Target: CHEK1 (Checkpoint Kinase 1 (CHEK1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHEK1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Product Details anti-CHEK1 Antibody

Binding Specificity: pSer345

Specificity: Phospho-Chk1 (S345) Polyclonal Antibody detects endogenous levels of Chk1 protein only when phosphorylated at S345.

Characteristics: Rabbit Polyclonal to Phospho-Chk1 (S345).

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human Chk1 around the phosphorylation site of S345.

Isotype: IgG

Application Details

Application Notes: IHC 1:100-1:300, ELISA 1:10000,

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C.

Target Details for CHEK1

Target: CHEK1 (Checkpoint Kinase 1 (CHEK1))

Alternative Name: Chk1

Molecular Weight: 56 kDa

Gene ID: 1111

UniProt: O14757

Pathways: p53 Signaling, Apoptosis, Cell Division Cycle, DNA Damage Repair