p53 antibody (pSer376)

Catalog No. ABIN3182905

The Rabbit Polyclonal anti-p53 antibody has been validated for IHC and ELISA. It is suitable to detect p53 in samples from Human, Mouse and Rat.

Quick Overview for p53 antibody (pSer376) (ABIN3182905)

Target: p53 (TP53) (Tumor Protein P53 (TP53))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This p53 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Product Details anti-p53 Antibody

Binding Specificity: pSer376

Specificity: Phospho-p53 (S376) Polyclonal Antibody detects endogenous levels of p53 protein only when phosphorylated at S376.

Characteristics: Rabbit Polyclonal to Phospho-p53 (S376).

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human p53 around the phosphorylation site of S376.

Isotype: IgG

Application Details

Application Notes: IHC 1:100-1:300, ELISA 1:5000,

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C.

Target Details for p53

Target: p53 (TP53) (Tumor Protein P53 (TP53))

Alternative Name: p53

Molecular Weight: 53 kDa

Gene ID: 7157

UniProt: P04637

Pathways: p53 Signaling, MAPK Signaling, PI3K-Akt Signaling, Apoptosis, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagy, Warburg Effect