JAK2 antibody (Tyr1007)
Quick Overview for JAK2 antibody (Tyr1007) (ABIN319309)
Target
See all JAK2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- Tyr1007
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Specificity
- This antibody detects endogenous levels of total JAK2 protein.
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Purification
- Immunoaffinity Chromatography.
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Immunogen
- The antiserum was produced against synthesized non-phosphopeptide derived from humanJAK2 around the phosphorylation site of Tyrosine 1007 (K-E-YP-Y-K).
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Application Notes
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Western Blot (1/500-1/1000).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Buffer
- PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- -20 °C
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Storage Comment
- Store the antibody (in aliquots) at-20 °C.
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- JAK2 (Janus Kinase 2 (JAK2))
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Alternative Name
- Tyrosine-Protein Kinase JAK2
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Background
- Synonyms: JAK-2, Janus kinase 2
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Gene ID
- 3717
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NCBI Accession
- NP_004963
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UniProt
- O60674
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Pathways
- JAK-STAT Signaling, RTK Signaling, Interferon-gamma Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Response to Growth Hormone Stimulus, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling, Unfolded Protein Response
Target
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