Integrin beta 2 antibody

Catalog No. ABIN3199545

This Mouse Monoclonal antibody specifically detects Integrin beta 2 in FACS, WB, IP and Func. It exhibits reactivity toward Human.

Quick Overview for Integrin beta 2 antibody (ABIN3199545)

Target: Integrin beta 2 (ITGB2)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Integrin beta 2 antibody is un-conjugated

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP), Functional Studies (Func)

Clone: MEM-148

Product Details anti-Integrin beta 2 Antibody

Specificity: Reacts with an epitope on human CD18 which is essentially inaccessible in intact integrin molecules on resting leukocytes, but exposed on high-affinity state of LFA-1 or on unassociated CD18

Cross-Reactivity: Pig (Porcine)

Cross-Reactivity (Details): Does not cross-react with porcine protein.

Purification: Purified (protein A)

Immunogen: Peripheral blood mononuclear cells

Isotype: IgG1

Application Details

Application Notes:

Working dilution: Optimal dilution should be determined by the end user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, pH 7.4, Sodium azide 15 mM

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2-8°C. Do not freeze.

Target Details for Integrin beta 2

Target: Integrin beta 2 (ITGB2)

Alternative Name: CD18

Gene ID: 3689

UniProt: P05107

Pathways: NF-kappaB Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation