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MCL-1 antibody
MCL1
Reactivity: Human
WB, ELISA, IHC, IF
Host: Mouse
Monoclonal
8C6-8C6D4B1
unconjugated
Product Details anti-MCL-1 Antibody
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Target
See all MCL-1 (MCL1) Antibodies
MCL-1 (MCL1)
(Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1))
Reactivity
All reactivities for MCL-1 antibodies
Human
Host
All hosts for MCL-1 antibodies
Mouse
Clonality
All clonalities for MCL-1 antibodies
Monoclonal
Conjugate
All conjugates for MCL-1 antibodies
This MCL-1 antibody is un-conjugated
Application
All applications for MCL-1 antibodies
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
Purification
Purified antibody.
Immunogen
MCL1 antibody was raised in Mouse using a purified recombinant fragment of human MCL-1 expressed in E. coli as the immunogen.
Clone
8C6-8C6D4B1
Isotype
IgG1
Top Product
Discover our top product MCL1 Primary Antibody
Alternatives
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Application Details
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Application Notes
ELISA: 1:10,000, IF: 1:200-1:1000, IHC: 1:200-1:1000, WB: 1:500-1:2000 Optimal conditions should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
Lot specific
Buffer
Purified antibody supplied in PBS containing 0.03 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Handling Advice
Avoid repeated freeze/thaw cycles. Dilute only prior to immediate use.
Storage
4 °C/-20 °C
Storage Comment
Store at 4 °C for short term storage. Store at -20 °C for long term storage.
Target Details for MCL-1
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Target
MCL-1 (MCL1)
(Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1))
Alternative Name
MCL1 (MCL1 Products )
Synonyms
BCL2L3 antibody, EAT antibody, MCL1-ES antibody, MCL1L antibody, MCL1S antibody, Mcl-1 antibody, TM antibody, bcl2-L-3 antibody, mcl1/EAT antibody, AW556805 antibody, mcl-1 antibody, fb72f02 antibody, wu:fb70a08 antibody, wu:fb72f02 antibody, zfMLP1 antibody, zfMcl-1a antibody, zgc:109835 antibody, zgc:109763 antibody, E3 antibody, E3-2 antibody, RNE3 antibody, RNU107 antibody, SNORA63A antibody, elF-4AII antibody, MCL1, BCL2 family apoptosis regulator antibody, myeloid cell leukemia sequence 1 antibody, MCL1, BCL2 family apoptosis regulator a antibody, MCL1, BCL2 family apoptosis regulator b antibody, small nucleolar RNA, H/ACA box 63 antibody, MCL1 antibody, Mcl1 antibody, mcl1a antibody, mcl1b antibody, SNORA63 antibody
Background
MCL1 is a protein which belongs to the Bcl-2 family. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. The longer gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene product (isoform 2) promotes apoptosis and is death-inducing. Synonyms: Monoclonal MCL1 antibody, Anti-MCL1 antibody, MCL-1 antibody, MCL 1 antibody, Myeloid cell leukemia 1 antibody.
Pathways
MAPK Signaling
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