Progesterone Receptor antibody

Catalog No. ABIN3210014

This Mouse Monoclonal antibody specifically detects Progesterone Receptor in WB, IHC and ELISA. It exhibits reactivity toward Human.

Quick Overview for Progesterone Receptor antibody (ABIN3210014)

Target: Progesterone Receptor (PGR)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Progesterone Receptor antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Clone: 2F12B4-2F12H2

Product Details anti-Progesterone Receptor Antibody

Immunogen: PR antibody was raised in Mouse using a purified recombinant fragment of PR expressed in E. coli as the immunogen.

Isotype: IgG1

Application Details

Application Notes: ELISA: 1:10,000, IHC: 1:200-1:1000, WB: 1:500-1:2000
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Supplied as a liquid in ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term storage. Store at -20 °C for long term storage.

Target Details for Progesterone Receptor

Target: Progesterone Receptor (PGR)

Alternative Name: PR

Background: PR is a member of the steroid receptor superfamily and mediates the physiologic effects of progesterone, PR is mediated by two functionally different isoforms of the progesterone receptor, the full length PR-B and the short form PR-A. The PR-A and PR-B proteins are 94 kDa and 114 kDa respectively. That are equimolar in the normal breast but dysregulated in advanced disease. PR is prognostic markers in breast cancers irrespective of the patient's progestational status Human progesterone. Synonyms: Monoclonal PR antibody, Anti-PR antibody, Progesterone Receptor antibody.

Pathways: Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration